High-Dimensional Feature Selection for Automatic Classification of Coronary Stenosis Using an Evolutionary Algorithm.

In this paper, a novel strategy to perform high-dimensional feature selection using an evolutionary algorithm for the automatic classification of coronary stenosis is introduced. The method involves a feature extraction stage to form a bank of 473 features considering different types such as intensity, texture and shape. The feature selection task is carried out on a high-dimensional feature bank, where the search space is denoted by O(2n) and n=473. The proposed evolutionary search strategy was compared in terms of the Jaccard coefficient and accuracy classification with different state-of-the-art methods. The highest feature selection rate, along with the best classification performance, was obtained with a subset of four features, representing a 99% discrimination rate. In the last stage, the feature subset was used as input to train a support vector machine using an independent testing set. The classification of coronary stenosis cases involves a binary classification type by considering positive and negative classes. The highest classification performance was obtained with the four-feature subset in terms of accuracy (0.86) and Jaccard coefficient (0.75) metrics. In addition, a second dataset containing 2788 instances was formed from a public image database, obtaining an accuracy of 0.89 and a Jaccard Coefficient of 0.80. Finally, based on the performance achieved with the four-feature subset, they can be suitable for use in a clinical decision support system.

3D Hermite Transform Optical Flow Estimation inLeft Ventricle CT Sequences.

Heart diseases are the most important causes of death in the world and over the years, thestudy of cardiac movement has been carried out mainly in two dimensions, however, it is important toconsider that the deformations due to the movement of the heart occur in a three-dimensional space.The 3D + t analysis allows to describe most of the motions of the heart, for example, the twistingmotion that takes place on every beat cycle that allows us identifying abnormalities of the heartwalls. Therefore, it is necessary to develop algorithms that help specialists understand the cardiacmovement. In this work, we developed a new approach to determine the cardiac movement inthree dimensions using a differential optical flow approach in which we use the steered Hermitetransform (SHT) which allows us to decompose cardiac volumes taking advantage of it as a model ofthe human vision system (HVS). Our proposal was tested in complete cardiac computed tomography(CT) volumes ( 3D + t), as well as its respective left ventricular segmentation. The robustness tonoise was tested with good results. The evaluation of the results was carried out through errors inforwarding reconstruction, from the volume at time t to time t + 1 using the optical flow obtained(interpolation errors). The parameters were tuned extensively. In the case of the 2D algorithm, theinterpolation errors and normalized interpolation errors are very close and below the values reportedin ground truth flows. In the case of the 3D algorithm, the results were compared with another similarmethod in 3D and the interpolation errors remained below 0.1. These results of interpolation errorsfor complete cardiac volumes and the left ventricle are shown graphically for clarity. Finally, a seriesof graphs are observed where the characteristic of contraction and dilation of the left ventricle isevident through the representation of the 3D optical flow.

A vision-based approach for fall detection using multiple cameras and convolutional neural networks: A case study using the UP-Fall detection dataset.

The automatic recognition of human falls is currently an important topic of research for the computer vision and artificial intelligence communities. In image analysis, it is common to use a vision-based approach for fall detection and classification systems due to the recent exponential increase in the use of cameras. Moreover, deep learning techniques have revolutionized vision-based approaches. These techniques are considered robust and reliable solutions for detection and classification problems, mostly using convolutional neural networks (CNNs). Recently, our research group released a public multimodal dataset for fall detection called the UP-Fall Detection dataset, and studies on modality approaches for fall detection and classification are required. Focusing only on a vision-based approach, in this paper, we present a fall detection system based on a 2D CNN inference method and multiple cameras. This approach analyzes images in fixed time windows and extracts features using an optical flow method that obtains information on the relative motion between two consecutive images. We tested this approach on our public dataset, and the results showed that our proposed multi-vision-based approach detects human falls and achieves an accuracy of 95.64% compared to state-of-the-art methods with a simple CNN network architecture.

Lack of Delta-Sarcoglycan (Sgcd) Results in Retinal Degeneration.

Age-related macular degeneration (AMD) is the leading cause of central vision loss and severe blindness among the elderly population. Recently, we reported on the association of the SGCD gene (encoding for δ-sarcoglycan) polymorphisms with AMD. However, the functional consequence of Sgcd alterations in retinal degeneration is not known. Herein, we characterized changes in the retina of the Sgcd knocked-out mouse (KO, Sgcd-/-). At baseline, we analyzed the retina structure of three-month-old wild-type (WT, Sgcd+/+) and Sgcd-/- mice by hematoxylin and eosin (H&E) staining, assessed the Sgcd-protein complex (α-, ß-, γ-, and ε-sarcoglycan, and sarcospan) by immunofluorescence (IF) and Western blot (WB), and performed electroretinography. Compared to the WT, Sgcd-/- mice are five times more likely to have retinal ruptures. Additionally, all the retinal layers are significantly thinner, more so in the inner plexiform layer (IPL). In addition, the number of nuclei in the KO versus the WT is ever so slightly increased. WT mice express Sgcd-protein partners in specific retinal layers, and as expected, KO mice have decreased or no protein expression, with a significant increase in the α subunit. At three months of age, there were no significant differences in the scotopic electroretinographic responses, regarding both a- and b-waves. According to our data, Sgcd-/- has a phenotype that is compatible with retinal degeneration.

UP-Fall Detection Dataset: A Multimodal Approach.

Falls, especially in elderly persons, are an important health problem worldwide. Reliable fall detection systems can mitigate negative consequences of falls. Among the important challenges and issues reported in literature is the difficulty of fair comparison between fall detection systems and machine learning techniques for detection. In this paper, we present UP-Fall Detection Dataset. The dataset comprises raw and feature sets retrieved from 17 healthy young individuals without any impairment that performed 11 activities and falls, with three attempts each. The dataset also summarizes more than 850 GB of information from wearable sensors, ambient sensors and vision devices. Two experimental use cases were shown. The aim of our dataset is to help human activity recognition and machine learning research communities to fairly compare their fall detection solutions. It also provides many experimental possibilities for the signal recognition, vision, and machine learning community.

Heart Rate Estimation using Hermite Transform Video Magnification and Deep Learning.

Monitoring of heart rate can be used in many medical and sports applications. Lack of portability and connection problems make traditional monitoring methods difficult to use outside of clinical environments. The computer vision techniques have been shown that some physiological variables as heart rate can be measured without contact. Video magnification is one of these approach used for the detection of the pulse signal. In this paper we propose a new strategy to magnify motion in a video sequence using the Hermite transform. In addition a deep learning technique is implemented to estimate the beat by beat pulse signal. We trained the system and validated our results using an electronic pulse monitoring device. Our approach is compared with the classical video magnification using a Gaussian pyramid. The results show a better enhancement of spectral information from the colour changes allowing an accurate estimation of the instantaneous beat by beat pulse than the Gaussian approach.

A Novel Artificial Organic Control System for Mobile Robot Navigation in Assisted Living Using Vision- and Neural-Based Strategies.

Robots in assisted living (RAL) are an alternative to support families and professional caregivers with a wide range of possibilities to take care of elderly people. Navigation of mobile robots is a challenging problem due to the uncertainty and dynamics of environments found in the context of places for elderly. To accomplish this goal, the navigation system tries to replicate such a complicated process inspired on the perception and judgment of human beings. In this work, we propose a novel nature-inspired control system for mobile RAL navigation using an artificial organic controller enhanced with vision-based strategies such as Hermite optical flow (OF) and convolutional neural networks (CNNs). Particularly, the Hermite OF is employed for obstacle motion detection while CNNs are occupied for obstacle distance estimation. We train the CNN using OF visual features guided by ultrasonic sensor-based measures in a 3D scenario. Our application is oriented to avoid mobile and fixed obstacles using a monocular camera in a simulated environment. For the experiments, we use the robot simulator V-REP, which is an integrated development environment into a distributed control architecture. Security and smoothness metrics as well as quantitative evaluation are computed and analyzed. Results showed that the proposed method works successfully in simulation conditions.

Segmentation and optical flow estimation in cardiac CT sequences based on a spatiotemporal PDM with a correction scheme and the Hermite transform.

PURPOSE: The left ventricle and the myocardium are two of the most important parts of the heart used for cardiac evaluation. In this work a novel framework that combines two methods to isolate and display functional characteristics of the heart using sequences of cardiac computed tomography (CT) is proposed. A shape extraction method, which includes a new segmentation correction scheme, is performed jointly with a motion estimation approach. METHODS: For the segmentation task we built a Spatiotemporal Point Distribution Model (STPDM) that encodes spatial and temporal variability of the heart structures. Intensity and gradient information guide the STPDM. We present a novel method to correct segmentation errors obtained with the STPDM. It consists of a deformable scheme that combines three types of image features: local histograms, gradients and binary patterns. A bio-inspired image representation model based on the Hermite transform is used for motion estimation. The segmentation allows isolating the structure of interest while the motion estimation can be used to characterize the movement of the complete heart muscle. RESULTS: The work is evaluated with several sequences of cardiac CT. The left ventricle was used for evaluation. Several metrics were used to validate the proposed framework. The efficiency of our method is also demonstrated by comparing with other techniques. CONCLUSION: The implemented tool can enable physicians to better identify mechanical problems. The new correction scheme substantially improves the segmentation performance. Reported results demonstrate that this work is a promising technique for heart mechanical assessment.